反应详情

The resultant compound of Example 11 (0.05 mmol) in 2 ml of pyridine was cooled to 0° C. and treated with 0.05 mmol of p-toluenesulfonyl chloride. After 2 h, the solution was diluted with ether, washed sequentially with 1N HCl, aqueous NaHCO3, and saturated brine, dried over MgSO4, and concentrated. Silica gel chromatography gave the desired compound.

1. washwashed sequentially with 1N HCl, aqueous NaHCO3, and saturated brine
2. dry with materialdried over MgSO4
3. concentrationconcentrated