HRID1379377

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID64800

Benzenepropanoic acid, .alpha.-(phenylmethyl)-

C16H16O2

HCID160435

Methanediimine

CH2N2

结构：CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)C(N)Cc1ccccc1

HCID14704377

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)Cc1ccccc1

HCID19431018

未命名化合物

PROCEDURE

实验过程

According to the carbodiimide coupling procedure of Example 55, dibenzylacetic acid was coupled to the resultant compound of Example 11 to give the desired compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fa22dd53d04a464fbb3431d1ca31ba9a
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05670675
来源说明: uspto-grants-1997_09

反应 SMILES

N=C=N.[CH2:4]([CH:11]([CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:12]([OH:14])=O)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[NH2:22][CH:23]([CH2:42][C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)[CH:24]([OH:41])[CH:25]([NH:33][C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[C:37]([O:36][C:34]([NH:33][CH:25]([CH:24]([OH:41])[CH:23]([NH:22][C:12](=[O:14])[CH:11]([CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:42][C:43]1[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=1)[CH2:26][C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1)=[O:35])([CH3:40])([CH3:38])[CH3:39]