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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1379377Generated: October 26, 2026

Benzenepropanoic acid, alpha-(phenylmethyl)- → 2(t-Butyloxycarbonylamino)-4-(N-(3-phenyl-2-(phenylmethyl)propionyl)amino)-1,5-diphenyl-3-hydroxypentane

https://huagongshe.com/reaction/1379377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanoic acid, alpha-(phenylmethyl)-HCID 64800—
ReactantCarbodiimideHCID 160435—
Reactant4-Amino-2-(t-butyloxycarbonylamino)-1,5-diphenyl-3-hydroxypentaneHCID 14704377—
Product2(t-Butyloxycarbonylamino)-4-(N-(3-phenyl-2-(phenylmethyl)propionyl)amino)-1,5-diphenyl-3-hydroxypentaneHCID 19431018—

Reaction Steps

According to the carbodiimide coupling procedure of Example 55, dibenzylacetic acid was coupled to the resultant compound of Example 11 to give the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05670675
Source datasetuspto-grants-1997_09
ORD IDord-fa22dd53d04a464fbb3431d1ca31ba9a
Source noteuspto-grants-1997_09