Benzyl Alcohol → HCID 11788946, compound

HRID 1379379Notes

Reaction equation

HRID 1379379 reaction equation
[CH:1]([C:4](=[CH2:8])[C:5]([OH:7])=[O:6])([CH3:3])[CH3:2].C1(N=C=NC2CCCCC2)CCCCC1.[CH2:24](O)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>CCOCC.CN(C)C1C=CN=CC=1>[CH:1]([C:4](=[CH2:8])[C:5]([O:7][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:6])([CH3:3])[CH3:2]

Participants

6

Reactant 3

HCID 244Benzyl AlcoholHCID 10868DicyclohexylcarbodiimideHCID 12122615alpha-Isopropylacrylic acid

Product 1

HCID 11788946HCID 11788946, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 3283Diethyl EtherSolvent

Procedure

α-Isopropylacrylic acid (13 mmol) in dry ether (40 ml) was treated with dicyclohexylcarbodiimide (12 mmol), benzyl alcohol (12 mmol) and 4-dimethylaminopyridine (2.5 mmol). After stirring at ambient temperature for 44 h, the mixture was filtered and evaporated. Silica gel chromatography provided the desired compound.

Workup

  1. filtrationthe mixture was filtered
  2. customevaporated

Sources & evidence

ORD record
ord-c3ad6ffd0e7047728f7f277f97e9d27a
Source dataset
uspto-grants-1997_09
Patent number
US05670675

Reaction notes

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