HuagongsheHuagongshe Chemistry Print Report · For research reference only
5'-O-(4,4'-Dimethoxytrityl)thymidine → 3'-O-(t-butyldimethylsilyl)thymidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5'-O-(4,4'-Dimethoxytrityl)thymidine | HCID 162419 | — |
| Reactant | N-(9-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide | HCID 136483518 | — |
| Product | 3'-O-(t-butyldimethylsilyl)thymidine | HCID 453844 | — |
Reaction Steps
This compound was prepared from 5'-O-(4,4'-dimethoxytrityl)-thymidine by the same procedure used for the preparation of 3'-O-t-butyldimethylsilyl-N2 -isobutyryl-2'-deoxyguanosine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05672697 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-ba677e714eaf4c4b96abe6ba5d83e478 |
| Source note | uspto-grants-1997_09 |