N2 Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine → N-(9-((2S,3R,4S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

Participants

Role	Name	HCID	Charge
Reactant	N2 Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine	HCID 136395924	—
Reactant	HCID 136395929	HCID 136395929	—
Product	N-(9-((2S,3R,4S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide	HCID 136395928	—

Reaction Steps

This compound is prepared from 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-N2 -isobutyrylguanine by the same procedure used for the preparation of N2 -isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05672697
Source dataset	uspto-grants-1997_09
ORD ID	ord-b6f70c1e54114e6e8ae9a7fd2f58e1fb
Source note	uspto-grants-1997_09