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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1379777Generated: October 26, 2026

N-Benzoyl-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine → 9-(3-O-t-Butyldimethylsilyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-N6-benzoyladenine

https://huagongshe.com/reaction/1379777

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Benzoyl-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosineHCID 11590906—
ReactantHCID 67563215HCID 67563215—
Product9-(3-O-t-Butyldimethylsilyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-N6-benzoyladenineHCID 54410811—

Reaction Steps

This compound is prepared from 9-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-2-fluoro-β-D-arabinofuranosyl]-N6 -benzoyladenine by the same procedure used for the preparation of 3'-O-t-butyldimethylsilyl-N6 -benzoyl-2'-deoxyadenosine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05672697
Source datasetuspto-grants-1997_09
ORD IDord-26c124c811b8464eabf0d5e3434a8dcd
Source noteuspto-grants-1997_09