反应详情

温度

0 °C

Combine 5-[(dimethylamino)methyl]-furfuryl alcohol (25 g) and dichloromethane (100 mL). Cool to 0° C. Add dropwise, thionyl chloride (20 mL) at such a rate that the reaction does not rise above 5° C. After 0.5 hours, evaporate in vacuo to give a residue, Recrystallize the residue from ethanol to give the title compound: mp; 164°-165° C. (dec).

1. additionAdd dropwise
2. customdoes not rise above 5° C
3. customevaporate in vacuo
4. customto give a residue
5. customRecrystallize the residue from ethanol