HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1379891Generated: November 2, 2026
Thionyl Chloride → 5-Dimethylaminomethylfurfuryl chloride hydrochloride
https://huagongshe.com/reaction/1379891
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-((Dimethylamino)methyl)-2-furanmethanol | HCID 84906 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-Dimethylaminomethylfurfuryl chloride hydrochloride | HCID 12954792 | — |
Reaction Steps
Combine 5-[(dimethylamino)methyl]-furfuryl alcohol (25 g) and dichloromethane (100 mL). Cool to 0° C. Add dropwise, thionyl chloride (20 mL) at such a rate that the reaction does not rise above 5° C. After 0.5 hours, evaporate in vacuo to give a residue, Recrystallize the residue from ethanol to give the title compound: mp; 164°-165° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05672724 |
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| Source dataset | uspto-grants-1997_09 |
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| ORD ID | ord-f93bd4428c1f4917982bfad123bb99b3 |
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| Source note | uspto-grants-1997_09 |
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