Ammonia → HCID 18943004, compound

HRID 1379910Notes

Reaction equation

HRID 1379910 reaction equation
[NH2:1][C:2]1[C:7]2[N:8]=C(N)[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.[OH-].[K+].[OH-].[Na+].N.Cl>C(O)(=O)C.O>[NH2:1][C:2]1[C:7]([NH2:8])=[C:6]([SH:10])[CH:5]=[CH:4][CH:3]=1

Participants

8

Reactant 5

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 14798Sodium HydroxideHCID 19608958HCID 19608958, compound

Product 1

HCID 18943004HCID 18943004, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Conditions

Temperature
260 °C

Procedure

The thus obtained bisaminobenzothiazole compound [II] is added to an aqueous solution of an alkali metal hydroxide such as potassium hydroxide or sodium hydroxide in an inert gas atomosphere at a temperature of about 110° to about 130° C., and then the mixture is slowly heated to about 260° C. to conduct reaction until generation of ammonia is ceased. Then, the temperature is lowered down to about 200° C. After addition of water thereto, the reaction mixture is cooled down to room temperature. Then, an aqueous dilute solution of an inorganic acid such as a concentrated hydrochloric acid is added to the reaction mixture to make pH 6, and then glacial acetic acid is added thereto to obtain a bisaminothiophenol compound [I] as precipitates.

Workup

  1. customis lowered down to about 200° C
  2. temperaturethe reaction mixture is cooled down to room temperature

Sources & evidence

ORD record
ord-e00149e131a24eda8e73880300445036
Source dataset
uspto-grants-1997_09
Patent number
US05672758

Reaction notes

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