HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → N[4(1-fluoromethyl-ethyl)phenyl]-formamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | 4(1-Fluoromethyl-ethyl)-aniline | HCID 13187368 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N[4(1-fluoromethyl-ethyl)phenyl]-formamide | HCID 13187377 | — |
Reaction Steps
A solution of 20 g (0.13 Mol) of 4(1-fluoromethyl-ethyl)benzeneamine and 6 g (0.13 Mol) of 98% formic acid in 150 ml of dry toluene is boiled under reflux. When 2.5 ml of water have separated in the water trap, an additional 6 g of formic acid are added and refluxing is continued until no more water and formic acid separate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04579585 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-fd676d0f19d94e62a36ed75b5f9c45ae |
| Source note | uspto-grants-1986_04 |