L-Cysteine hydrochloride monohydrate → HCID 57006158, compound

Participants

Reaction Steps

A solution of 3.3 g of methyl-[3-(2-oxo-4-phenyl-3-imidazolidinyl)propylthio]formate and 1.8 g of L-cysteine hydrochloride hydrate in 80 ml of methanol is refluxed under nitrogen for three hours. The solvent is removed in vacuo and the residue triturated with ether yielding a hygroscopic solid. The product is further purified by conversion to its 4-methyl benzene sulfonic acid salt, m.p. 172°-178° C.

Provenance & Evidence