Lithium aluminum hydride → HCID 20241749, compound

HRID 1380044Notes

Reaction equation

HRID 1380044 reaction equation
[AlH4-].[Li+].[O:3]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[O:6][CH2:5][CH:4]1[CH:13]([N:15]1[CH2:20][CH2:19][CH:18]([C:21]([NH2:23])=O)[CH2:17][CH2:16]1)[CH3:14]>O1CCCC1>[O:3]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[O:6][CH2:5][CH:4]1[CH:13]([N:15]1[CH2:16][CH2:17][CH:18]([CH2:21][NH2:23])[CH2:19][CH2:20]1)[CH3:14]

Participants

4

Reactant 2

HCID 28112Lithium aluminum hydrideHCID 20241751HCID 20241751, compound

Product 1

HCID 20241749HCID 20241749, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a suspension of 30 g lithium aluminohydride in 1000 ml tetrahydrofuran 78 g of the carboxamide of step F as the solid is added thereto portionwise.

Workup

  1. additionis added

Sources & evidence

ORD record
ord-80905df5e618452d9e577fd0a42ac987
Source dataset
uspto-grants-1986_04
Patent number
US04579845

Reaction notes

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