HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 1,3-Benzoxazol-7-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Catecholamine | HCID 189460 | — |
| Product | 1,3-Benzoxazol-7-ol | HCID 20242116 | — |
Reaction Steps
A mixture of 2,3-dihydroxyaniline (2.5 g.), triethylorthoformate (4.5 g.) and 0.1 g. sulfuric acid is heated at 130° C. for one hour. After cooling, the remaining material is purified by HPLC on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04579865 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-7720a76b41924fb2be5a4377869cf05b |
| Source note | uspto-grants-1986_04 |