HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitrogen → 1,1-Dichloroethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitrogen | HCID 947 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Dihydropyridines | HCID 407038 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1,1-Dichloroethane | HCID 6365 | — |
| Product | Anisole | HCID 7519 | — |
Reaction Steps
Dihydropyridine 2 (R8 =CH2 -C6H5 or ##STR4## Y=O or S, n=0 or 1) (Reaction Scheme I) is treated under an inert atmosphere (Ar or N2) with about 5-50 meq (preferably 10 meq trifluoroacetic acid neat or in the presence of a solvent (anisole, CH2Cl2, CHCl3, dichloroethane) at 25°-100° C. (preferably 25° C.) for about 10-60 minutes to obtain the Formula 1 compound. ##STR5##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04579851 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-0f066fe2f82144649d19667513a800d0 |
| Source note | uspto-grants-1986_04 |