1-(2-Bromoethyl)-4-methoxybenzene → 1-Methoxy-4-(pent-4-en-1-yl)benzene

HRID 1380127Notes

Reaction equation

HRID 1380127 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:6]([CH2:7][CH2:8][Mg]Br)=[CH:5][CH:4]=1.CO[C:15]1[CH:23]=CC(CCBr)=C[CH:16]=1.[Mg]>>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:6]([CH2:7][CH2:8][CH2:23][CH:15]=[CH2:16])=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 844271-(2-Bromoethyl)-4-methoxybenzeneHCID 5462224MagnesiumHCID 178490220HCID 178490220, compound

Product 1

HCID 133952001-Methoxy-4-(pent-4-en-1-yl)benzene

Procedure

This compound was prepared as in Example 35a using 4-methoxyphenethyl magnesium bromide prepared from 4-methoxyphenethyl bromide and magnesium turnings. The crude oil isolated after work-up was distilled to give the title compound (b.p. 65° C., 0.3 mm.Hg), as a colourless oil.

Workup

  1. customThis compound was prepared as in Example 35a
  2. customThe crude oil isolated after work-up
  3. distillationwas distilled

Sources & evidence

ORD record
ord-de0affe0b6de48ebaf00fb82f29584ce
Source dataset
uspto-grants-1986_04
Patent number
US04579862

Reaction notes

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