HCID 23326372, compound → HCID 19017775, compound

Participants

Reaction Steps

1-Benzyl-2-amino-4,7-dimethoxybenzimidazole (17.85 g, 0.06 mole) is hydrogenated in the presence of palladium on carbon catalyst (10%) at 50 psi for about twelve hours. After filtration the methanol is removed in vacuo and the residue dissolved in boiling water and treated with decolorizing charcoal. The suspension is filtered into 1N NaOH, giving a white precipitate of 2-amino-4,7-dimethoxybenzimidazole. The amorphous white powder melts at 251°-253° C.

Provenance & Evidence