HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(Trifluoromethyl)prop-2-enoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(Trifluoromethyl)acrylic acid | HCID 587694 | — |
| Product | 2-(Trifluoromethyl)prop-2-enoyl chloride | HCID 10149016 | 66% |
Reaction Steps
Thionyl chloride (11.5 ml; 158 mmoles) was added to α-trifluoromethylacrylic acid (19.7 g; 141 mmoles), and the mixture was heated under reflux for 22 hours. Distillation of the reaction mixture under atmospheric pressure gave 14.7 g (yield:66%) of α-trifluoromethylacryloyl chloride, B.p. 89°-90° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04581452 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-195be3943dd040cbb074eb4ba395e34a |
| Source note | uspto-grants-1986_04 |