反应详情

3.5 g of 5-(4-methoxyphenyl)-4-methyl-2-(1H)-pyrimidinone are dissolved in methanol, the solution is acidified with ethereal hydrochloric acid (pH 2-3), and ether is added to incipient opalescence. The solution is cooled and the crystals are filtered off with suction. After drying, 3.3 g of 5-(4-methoxyphenyl)-4-methyl-2-(1H)-pyrimidinone hydrochloride are obtained. Melting point 265° C. (decomposition).

1. additionis added to incipient opalescence
2. temperatureThe solution is cooled
3. filtrationthe crystals are filtered off with suction
4. customAfter drying