Triethylamine → HCID 86740724, compound

HRID 1380544Notes

Reaction equation

HRID 1380544 reaction equation
[CH2:1]([N:4]1[C:8](=[O:9])[CH:7]([OH:10])[S:6][C:5]1=[N:11][N:12]=[C:13]1[N:17]([CH3:18])[C:16](=[O:19])[CH2:15][S:14]1)[CH:2]=[CH2:3].Cl[P:21]1(=[O:27])[N:25]([CH3:26])[CH2:24][CH2:23][O:22]1.C(N(CC)CC)C>C(Cl)Cl>[CH2:1]([N:4]1[C:8](=[O:9])[CH:7]([O:10][P:21]2(=[O:27])[N:25]([CH3:26])[CH2:24][CH2:23][O:22]2)[S:6][C:5]1=[N:11][N:12]=[C:13]1[N:17]([CH3:18])[C:16](=[O:19])[CH2:15][S:14]1)[CH:2]=[CH2:3]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 14553006HCID 14553006, compoundHCID 54502065HCID 54502065, compound

Product 1

HCID 86740724HCID 86740724, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In a manner analogous to that described in Example 24 starting from 7.5 g (0.025 mol) of 3-allyl-5-hydroxy-2-[[3-methyl-4-oxo-2-thiazolidinylidene]-hydrazono]-4-thiazolidinone, 7.8 g (0.05 mol) of 2-chloro-3-methyl-1,3,2-oxazaphospholidine-2-oxide and 4.53 ml (0.0325 mol) of triethylamine in 50 ml of methylene chloride there is obtained 2-[3-allyl-2-[[3-methyl-4-oxo-2-thiazolidinylidene]-hydrazono]-4-oxo-5-thiazol-idinoxy]-3-methyl-2-oxo-1,3,2-oxazaphospholidine having a melting point of 184°-185°.

Sources & evidence

ORD record
ord-c1fa67fbca1b4f04a67cd34fd262753e
Source dataset
uspto-grants-1986_04
Patent number
US04582841

Reaction notes

Loading…