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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1380597Generated: October 26, 2026

Morpholine → 2-Methyl-1-(4-(methylthio)phenyl)-2-morpholino-1-propanone

https://huagongshe.com/reaction/1380597

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant2-Methoxy-3,3-dimethyl-2-(4-methylsulfanylphenyl)oxiraneHCID 20192525—
Product2-Methyl-1-(4-(methylthio)phenyl)-2-morpholino-1-propanoneHCID 92387—

Reaction Steps

151.4 g (0.675 mol) of 3,3-dimethyl-2-methoxy-2-[4-(methylthio)-phenyl]-oxirane (melting point 62°-64° C.) are dissolved in 235.2 g (2.70 mols) of morpholine and the solution is warmed to reflux temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04582862
Source datasetuspto-grants-1986_04
ORD IDord-4ecf9a967c7d4b6baebe3047e916cac9
Source noteuspto-grants-1986_04