Acetic Acid → HCID 12783078, compound

HRID 1380774Notes

Reaction equation

HRID 1380774 reaction equation
[CH3:1][C:2]([CH3:14])([C:11](=[O:13])[CH3:12])[CH2:3][S:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.OO.[OH2:17].C(O)(=[O:20])C>>[CH3:1][C:2]([CH3:14])([C:11](=[O:13])[CH3:12])[CH2:3][S:4]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)(=[O:20])=[O:17]

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 962WaterHCID 10822274HCID 10822274, compound

Product 1

HCID 12783078HCID 12783078, compoundYield 84.2%

Conditions

Temperature
50 °C

Procedure

40.6 g (0.2 mole) of 2,2-dimethyl-1-phenylmercapto-butan-3-one (Example 4) were dissolved in 300 ml of glacial acetic acid, and 30.4 g (0.89 mole) of hydrogen peroxide were added. The reaction mixture was stirred at 50° C. for 8 hours. It was then poured into 250 ml of water and extracted with ether. The ether phase was washed with sodium bicarbonate solution, and with water, until neutral, and dried over sodium sulphate and concentrated. 40.4 g (84.2% of theory) of 2,2-dimethyl-1-phenylsulphonyl-butan-3-one of melting point 56°-58° C. were obtained.

Workup

  1. extractionextracted with ether
  2. washThe ether phase was washed with sodium bicarbonate solution
  3. dry with materialwith water, until neutral, and dried over sodium sulphate
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-a1cb57f980774bfbba3f0182c0521dd9
Source dataset
uspto-grants-1986_04
Patent number
USRE032122

Reaction notes

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