Isopropanol → HCID 23324653, compound

Participants

Reaction Steps

6-Chloro-4-chloromethyl-2-isopropyl-pyrimidine (see Example 61) is reacted with isopropanol and sodium analogously to the process described in Example 62 in order to produce 4-chloromethyl-2-isopropyl-6-isopropoxy-pyrimidine which is required as the starting material in Example 22. This product is obtained in the form of an oil, 1H-NMR (CDCl3): 1.30 (d, 2×CH3), 1.37 (d, 2×CH3), 3.10 (m, CH), 4.50 (s, CH), 5.40 (m, CH), 6.65 (s, CH).

Provenance & Evidence