Dimethylcarbamoyl Chloride → HCID 23324649, compound

HRID 1380837Notes

Reaction equation

HRID 1380837 reaction equation
[CH2:1]([O:3][C:4]1[N:9]=[C:8]([CH2:10][Cl:11])[CH:7]=[C:6]([OH:12])[N:5]=1)[CH3:2].[CH3:13][N:14]([CH3:18])[C:15](Cl)=[O:16]>>[CH3:13][N:14]([CH3:18])[C:15](=[O:16])[O:12][C:6]1[N:5]=[C:4]([O:3][CH2:1][CH3:2])[N:9]=[C:8]([CH2:10][Cl:11])[CH:7]=1

Participants

3

Reactant 2

HCID 6598Dimethylcarbamoyl ChlorideHCID 178467470HCID 178467470, compound

Product 1

HCID 23324649HCID 23324649, compound

Procedure

2-Ethoxy-4-chloromethyl-6-hydroxy-pyrimidine is reacted with N,N-dimethylcarbamoyl chloride analogously to the process described in Example 87 in order to produce 2-ethoxy-4-chloromethyl-6-pyrimidinyl N,N-dimethylcarbamate which is required as the starting material in Example 33. This product is obtained in the form of a yellow oil, 1H-NMR (CDCl3): 1.43 (t, OCH2CH3), 3.08 and 3.14 (2×s, CON(CH3)2), 4.40 (q, OCH2CH3), 4.50 (s, CH2Cl), 7.00 (s, CH).

Sources & evidence

ORD record
ord-bca6e22576e54ab78c7c2083eb9be363
Source dataset
uspto-grants-1986_04
Patent number
US04584295

Reaction notes

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