Sodium Hydroxide → HCID 23324631, compound

Participants

Reaction Steps

A solution of 1.6 g (0.0059 mol) of 4-acetoxymethyl-2,6-diethylthio-pyrimidine in 3 ml of ethanol is treated at 0° C. with a solution of 0.86 g (0.0065 mol) of sodium hydroxide in 2.5 ml of ethanol. After 5 minutes the mixture is diluted with 150 ml of diethyl ether and washed neutral with water. The organic phase is dried over anhydrous magnesium sulphate and evaporated. In this manner there is obtained as the residue 2,6-diethylthio-4-hydroxymethyl-pyrimidine.

Provenance & Evidence