Acetic Acid → HCID 13520695, compound

HRID 1380855Notes

Reaction equation

HRID 1380855 reaction equation
CO[C:3]1[C:4]([CH2:14][C:15]#[N:16])=[C:5]([CH2:11][C:12]#[N:13])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[BrH:17].[C:18]([OH:21])(=O)C>>[BrH:17].[CH3:18][O:21][C:7]1[C:8]([O:9][CH3:10])=[CH:3][C:4]2[CH2:14][C:15]([NH2:16])=[N:13][C:12]([Br:17])=[CH:11][C:5]=2[CH:6]=1

Participants

4

Reactant 3

HCID 176Acetic Acid2×HCID 260Hydrogen BromideHCID 100362453,4-Dimethoxy-1,2-benzenediacetonitrile

Product 1

HCID 13520695HCID 13520695, compound

Procedure

First 3,4-dimethoxy-o-phenylene-diacetonitrile (3.7 g, 0.017 mol) is suspended in glacial acetic acid (10 ml) and 30% hydrobromic acid in glacial acetic acid (12 ml) is added at 20° C. Then, the mixture is stirred for 3 hours at ambient temperature. The precipitate obtained is suction filtered, washed with glacial acetic acid and then with acetone/ether and dried. Yield: 5.3 g. Mp: 210°-211° C. (Decomp.)

Workup

  1. customThe precipitate obtained
  2. filtrationfiltered
  3. washwashed with glacial acetic acid
  4. dry with materialwith acetone/ether and dried

Sources & evidence

ORD record
ord-c315312587d84d9186ffe86959c7b9e6
Source dataset
uspto-grants-1986_04
Patent number
US04584293

Reaction notes

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