3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → 1-[7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(8-methoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane

Participants

Role	Name	HCID	Charge
Reactant	3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one	HCID 13092510	—
Reactant	8-Methoxy-2-methylamino-1,2,3,4-tetrahydronaphthalene	HCID 13579647	—
Solvent	Triethylamine	HCID 8471	—
Product	1-[7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(8-methoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane	HCID 13579655	—

Reaction Steps

The title compound is prepared analogously to Example 1 by reacting 1-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-3-chloropropane, triethylamine and 8-methoxy-2-methylamino-1,2,3,4-tetrahydronaphthalene. Mp: 141°-143° C. (decomp.).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04584293
Source dataset	uspto-grants-1986_04
ORD ID	ord-ff4b78003f1a430899b06b3d68803ffb
Source note	uspto-grants-1986_04