HCID 13579648, compound → 1-[7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-3-yl]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane

HRID 1380896Notes

Reaction equation

HRID 1380896 reaction equation
[CH3:1][O:2][C:3]1[C:33]([O:34][CH3:35])=[CH:32][C:6]2[CH2:7][C:8](=O)[N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:30])[CH:16]3[CH2:25][CH2:24][C:23]4[C:18](=[CH:19][C:20]([O:28][CH3:29])=[C:21]([O:26][CH3:27])[CH:22]=4)[CH2:17]3)[CH:10]=[CH:11][C:5]=2[CH:4]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH3:35][O:34][C:33]1[C:3]([O:2][CH3:1])=[CH:4][C:5]2[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14][N:15]([CH3:30])[CH:16]3[CH2:25][CH2:24][C:23]4[C:18](=[CH:19][C:20]([O:28][CH3:29])=[C:21]([O:26][CH3:27])[CH:22]=4)[CH2:17]3)[CH:8]=[CH:7][C:6]=2[CH:32]=1

Participants

3

Reactant 2

HCID 13579648HCID 13579648, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 233245791-[7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-3-yl]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane

Procedure

The title compound is prepared from 1-[7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane and lithium aluminum hydride analogously to Example 13. Mp: 115°-116° C.

Sources & evidence

ORD record
ord-e5912dcead3744118186183f02c17021
Source dataset
uspto-grants-1986_04
Patent number
US04584293

Reaction notes

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