Androstenedione → 9alpha-Hydroxyandrost-4-ene-3,17-dione

Participants

Reaction Steps

We have carried on investigations with attention to the fact that corticoids can be prepared through fewer steps from the aforementioned androst-4-ene-3,17-dione, androsta-1,4-diene-3,17-dione or androsta-4,9(11) -diene-3,17-dione which has recently be produced inexpensively and in a large scale from 9α-hydroxy-androst-4ene-3,17-dione which has also recently be produced by a fermentative process.

Provenance & Evidence