反应详情

5 g of the 1-methyl-3-phenoxypropyldiethylamine was reacted with 30 ml of 40% hydrobromic acid at 150° C. for 7 hours with stirring. The reaction solution was cooled, 20 ml of chloroform and was added and then the solution was separated into two phases, which phases were then separated from each other. The hydrobromic acid was removed under reduced pressure and the residue was recrystallized from 5 ml of ethyl alcohol to give 4.88 g of 1-methyl-3-bromopropyldiethylamine hydrobromide in a yield of 78%.

1. temperatureThe reaction solution was cooled
2. customthe solution was separated into two phases, which phases
3. customwere then separated from each other
4. customThe hydrobromic acid was removed under reduced pressure
5. customthe residue was recrystallized from 5 ml of ethyl alcohol