Hydrochloric Acid → 3-(2-Piperidinoethylamino)indazole hydrochloride

HRID 1381307Notes

Reaction equation

HRID 1381307 reaction equation
[N:1]1([CH2:7][CH2:8][NH:9][C:10]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[NH:12][N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:19]>C(O)C>[ClH:19].[N:1]1([CH2:7][CH2:8][NH:9][C:10]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[NH:12][N:11]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 30680421H-Indazol-3-amine, N-(2-(1-piperidinyl)ethyl)-

Product 1

HCID 233240393-(2-Piperidinoethylamino)indazole hydrochloride

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 50 ml of absolute ethyl alcohol was dissolved 4.0 g of 3-(2-piperidinoethylamino)indazole and into the solution was introduced dried hydrogen chloride gas under cooling with ice. Anhydrous diethyl ether to separate crystals. Then the crystals were obtained by filtration and dried to give 3-(2-piperidinoethylamino)indazole hydrochloride.

Workup

  1. temperatureunder cooling with ice
  2. customAnhydrous diethyl ether to separate crystals
  3. customThen the crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-159c1257d5834bdbb0f0703901689e43
Source dataset
uspto-grants-1986_04
Patent number
US04585869

Reaction notes

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