Hydrochloric Acid → HCID 23324098, compound

HRID 1381310Notes

Reaction equation

HRID 1381310 reaction equation
[N:1]1([CH2:7][CH2:8][N:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]([NH2:18])=[N:10]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:19].C(OCC)C>C(O)C>[ClH:19].[ClH:19].[N:1]1([CH2:7][CH2:8][N:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]([NH2:18])=[N:10]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 3028863HCID 3028863, compound

Product 1

HCID 23324098HCID 23324098, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 15 ml of absolute ethyl alcohol was dissolved 1.28 g of 1-(2-piperidinoethyl)-3-aminoindazole and into the solution was introduced dried hydrogen chloride gas under cooling with ice. Anhydrous diethyl ether was added to the solution to separate crystals. Then the crystals were obtained by filtration and dried to give 1-(2-piperidinoethyl)-3-aminoindazole dihydrochloride.

Workup

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThen the crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-e1e1da81e9c84331873325d917519cb0
Source dataset
uspto-grants-1986_04
Patent number
US04585869

Reaction notes

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