Benzaldehyde → 3-Bromobenzaldehyde
Reaction equation
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.BrCl.[Cl-].[Al+3].[Cl-].[Cl-].[Br:15]CBr>>[Br:15][C:4]1[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=1)[CH:1]=[O:8]Participants
5
Procedure
A process which comprises reacting one molar proportion of benzaldehyde with about 0.9-1.2 molar proportions of bromine chloride in the presence of about 1.1-2.2 molar proportions of aluminum chloride and about 0.3-0.9 mol of dibromomethane per mol of aluminum chloride under substantially anhydrous conditions at a temperature in the range of about 40°-95° C. so as to form 3-bromobenzaldehyde, the components of the reaction mixture being combined by gradually adding the bromine chloride to a dibromomethane slurry of the benzaldehyde and aluminum chloride.
Workup
- customin the range of about 40°-95° C.
Sources & evidence
- ORD record
- ord-734cb648d17f4abcbb0f878f6f79603c
- Source dataset
- uspto-grants-1986_04
- Patent number
- US04585898
Reaction notes
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