Acetic Anhydride → HCID 13893921, compound

HRID 1381375Notes

Reaction equation

HRID 1381375 reaction equation
[OH:1][C:2]1[C:6](=[O:7])[O:5][CH:4]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[C:19](OC(=O)C)(=[O:21])[CH3:20]>N1C=CC=CC=1>[C:19]([O:1][C:2]1[C:6](=[O:7])[O:5][CH:4]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=[O:21])[CH3:20]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 1283563-(4-Hydroxy-5-oxo-3-phenyl-2,5-dihydrofuran-2-yl)propanoic acid

Product 1

HCID 13893921HCID 13893921, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

3-(4-Hydroxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)-propionic acid (100 mg) was dissolved in pyridine (2 ml), and acetic anhydride (1 ml) was added. The mixture was allowed to stand overnight. The excess reagent and solvent were removed by distillation under reduced pressure, and the residue was dried to give 3-(4-acetoxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)propionic acid (116 mg) as an oil.

Workup

  1. customThe excess reagent and solvent were removed by distillation under reduced pressure
  2. customthe residue was dried

Sources & evidence

ORD record
ord-5b7d2907bcc04a978f8b91fd38a09b55
Source dataset
uspto-grants-1986_04
Patent number
US04585789

Reaction notes

Loading…