Methanol → HCID 13893920, compound

HRID 1381378Notes

Reaction equation

HRID 1381378 reaction equation
O[C:2]1[C:6](=[O:7])[O:5][CH:4]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[N+](=[CH2:21])=[N-].[CH3:22][OH:23]>CCOCC>[CH3:22][O:23][C:2]1[C:6](=[O:7])[O:5][CH:4]([CH2:8][CH2:9][C:10]([O:12][CH3:21])=[O:11])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 9550DiazomethaneHCID 1283563-(4-Hydroxy-5-oxo-3-phenyl-2,5-dihydrofuran-2-yl)propanoic acid

Product 1

HCID 13893920HCID 13893920, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

3-(4-Hydroxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)propionic acid (100 mg) was dissolved in methanol (2 ml), and a solution of diazomethane in ether was added thereto until the yellow color did not vanish any longer. The mixture was allowed to stand at room temperature overnight. The solvent was then distilled off to give methyl 3-(4-methoxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)propionate (110 mg).

Workup

  1. distillationThe solvent was then distilled off

Sources & evidence

ORD record
ord-ed98f40003de4e4986362a7921d187cc
Source dataset
uspto-grants-1986_04
Patent number
US04585789

Reaction notes

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