Sodium ethoxide → HCID 178489578, compound

HRID 1381543Notes

Reaction equation

HRID 1381543 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]1[CH2:14][CH2:13][N:12](S(C2C=CC(C)=CC=2)(=O)=O)[N:11]=1.[O-]CC.[Na+]>O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]1[CH:14]=[CH:13][NH:12][N:11]=1

Participants

4

Reactant 2

HCID 2723922Sodium ethoxideHCID 178489585HCID 178489585, compound

Product 1

HCID 178489578HCID 178489578, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The product of step (a) (7.5 g) was added to a solution of sodium ethoxide (60 ml, prepared from 0.6 g sodium), at a temperature of 60°. The mixture was refluxed for 10 minutes, cooled, added to water, extracted with ethyl acetate, dried and evaporated to give the sub-title compound as a purple oil, ms 189 (M+).

Workup

  1. temperatureThe mixture was refluxed for 10 minutes
  2. temperaturecooled
  3. extractionextracted with ethyl acetate
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-52fba63b6f094fad8d0e0627c77951d2
Source dataset
uspto-grants-1989_02
Patent number
US04803216

Reaction notes

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