Hydrochloric Acid → HCID 14350447, compound

HRID 1381663Notes

Reaction equation

HRID 1381663 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[O:15])[C:8](=[N:13]O)[C:9](=[O:12])[CH2:10][CH3:11])=[CH:3][CH:2]=1.[H][H].Cl>C(O)(=O)C.[Pd]>[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([OH:15])[CH:8]([NH2:13])[C:9](=[O:12])[CH2:10][CH3:11])=[CH:3][CH:2]=1

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 178418361HCID 178418361, compoundHCID 178459333HCID 178459333, compound

Product 1

HCID 14350447HCID 14350447, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

In 1000 ml acetic acid was dissolved 23.0 g (0.11 mol) of 1-(4-pyridyl)-1,3-diketo-2-oximinopentane. The solution is charged with 1.0 g of 10% palladium on carbon and hydrogenated until three equivalents of hydrogen were taken up. The mixture was acidified with 18.5 ml of 12N hydrochloric acid, filtered and the solvent evaporaed to give the title compound as the dihydrochloric acid salt; m.p. 225° C.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-04aec3e4d7414269a42c59c3dcb1c019
Source dataset
uspto-grants-1989_02
Patent number
US04803278

Reaction notes

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