Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 11804905 | HCID 11804905 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21276499 | HCID 21276499 | 94% |
Reaction Steps
To an ice-cooled solution of 1.26 g (0.0086 mol) of product from Step C and 1.44 g (0.0142 mol) of triethylamine in 25 ml of methylene chloride was added dropwise 0.75 g (0.0095 mol) of acetyl chloride. The solution was stirred for four hours at 0° C., after which time it was washed with water, a saturated solution of sodium bicarbonate, and water. The organic phase was dried (MgSO4), filtered, and evaporated to give 1.52 g (94%) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04803286 |
|---|
| Source dataset | uspto-grants-1989_02 |
|---|
| ORD ID | ord-7998e6bddfaa4b2c822fb428ef61ea9e |
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| Source note | uspto-grants-1989_02 |
|---|
