2-Amino-2-methyl-1,3-propanediol → HCID 13375291, compound

HRID 1381738Notes

Reaction equation

HRID 1381738 reaction equation
[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH:17]=O)[C:8]3[C:13]([C:14]=2[Cl:16])=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1.[CH3:19][C:20]([NH2:25])([CH2:23][OH:24])[CH2:21][OH:22]>>[ClH:1].[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH2:17][NH:25][C:20]([CH3:19])([CH2:23][OH:24])[CH2:21][OH:22])[C:8]3[C:13]([C:14]=2[Cl:16])=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 13375395HCID 13375395, compound

Product 1

HCID 13375291HCID 13375291, compound

Procedure

Using the reductive amination procedure outlined in 1, 4,10-dichloro-9-anthracenecarbaldehyde and 2-methyl-2-amino-1,3-propanediol (Aldrich) gave 2-((4,10-dichloro-9-anthracenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride mp 261°-262° (dec.), (EtOH/Et2O), (C, H, Cl, N).

Sources & evidence

ORD record
ord-bd6ecb99d331467397c0d6a23689efc9
Source dataset
uspto-grants-1989_02
Patent number
US04803226

Reaction notes

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