2-Amino-2-methyl-1,3-propanediol → HCID 14391230, compound

HRID 1381801Notes

Reaction equation

HRID 1381801 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:13]2[C:4](=[C:5]([CH:18]=O)[C:6]3[C:11]([C:12]=2[Cl:16])=[CH:10][C:9]([Cl:17])=[CH:8][CH:7]=3)[CH:3]=1.[NH2:20][C:21]([CH3:26])([CH2:24][OH:25])[CH2:22][OH:23]>>[ClH:1].[CH3:26][C:21]([NH:20][CH2:18][C:5]1[C:6]2[C:11]([C:12]([Cl:16])=[C:13]3[C:4]=1[CH:3]=[C:2]([Cl:1])[CH:15]=[CH:14]3)=[CH:10][C:9]([Cl:17])=[CH:8][CH:7]=2)([CH2:24][OH:25])[CH2:22][OH:23]

Participants

3

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 14391244HCID 14391244, compound

Product 1

HCID 14391230HCID 14391230, compound

Procedure

Using the reductive amination procedure outlined in 1, 2,6,10-trichloroanthracene-9-carbaldehyde (43B) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-methyl-2-(((2,6,10-trichloro-9-anthracenyl)methyl)amino)-1,3-propanediol hydrochloride mp 275°-277° (dec), (EtOH/Et2O), (C, H, Cl, N).

Sources & evidence

ORD record
ord-bf19e35c33174f41b943014adfb11ddf
Source dataset
uspto-grants-1989_02
Patent number
US04803221

Reaction notes

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