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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1381811Generated: November 2, 2026

2-Isopropyl-2-nitro-1,3-propanediol acetate → 2-Amino-2-isopropyl-1,3-propanediol acetate

https://huagongshe.com/reaction/1381811

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Isopropyl-2-nitro-1,3-propanediol acetateHCID 53848015—
Reactant(+-)(2R*,3R*)-2-amino-2-methyl-1,3-butanediol acetateHCID 86741969—
Product2-Amino-2-isopropyl-1,3-propanediol acetateHCID 14391248—

Reaction Steps

Using the procedure in 5E, 2-isopropyl-2-nitro-1,3-propanediol acetate mp 155°-155.5°. H. S. Broadbent et al., J. Heterocyclic Chem., 13, 337 (1975) report the synthesis of this compound as the free base (mp 70°-72°)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04803222
Source datasetuspto-grants-1989_02
ORD IDord-de273b80cc5141ef8c305e8934962dfb
Source noteuspto-grants-1989_02