HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 10751498, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 10751498 | HCID 10751498 | — |
Reaction Steps
Add 25.0g (0.158 mol) of p-fluorobenzoyl chloride drop-wise to a 0° C. solution of 15.0 g (0.150 mol) of N-methylpiperazine and 20.0 g (0.189 mol) of sodium carbonate in 100 mL of water. Stir the resultant solution at 0° C. for about 30 minutes, then at room temperature for about 2 hr. Extract the resultant solution with methylene chloride (2×100 mL). Dry the combined extracts with Na2SO4 and evaporate the solvent to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04804662 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-7ab1e909f8e04f358266d4fbc20b9ac9 |
| Source note | uspto-grants-1989_02 |