Hydrogen Bromide → HCID 131715860, compound

HRID 1381964Notes

Reaction equation

HRID 1381964 reaction equation
C(OC([N:11]1[CH2:24][CH2:23][C:14]2([C:18](=[O:19])[N:17]([O:20][CH3:21])[C:16](=[S:22])[CH2:15]2)[CH2:13][CH2:12]1)=O)C1C=CC=CC=1.C(OCC)C.[BrH:30]>C(O)(=O)C>[BrH:30].[CH3:21][O:20][N:17]1[C:16](=[S:22])[CH2:15][C:14]2([CH2:23][CH2:24][NH:11][CH2:12][CH2:13]2)[C:18]1=[O:19]

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 3283Diethyl EtherHCID 14371883HCID 14371883, compound

Product 1

HCID 131715860HCID 131715860, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In an acetic acid solution (5 ml) of 25% hydrogen bromide was dissolved 8-benzyloxycarbonyl-2-methoxy-2,8-diazaspiro[4,5]decane-3-thion-1-one (0.5 g), and the solution was left standing at room temperature for 20 minutes. To the solution was added ethyl ether (100 ml), and resulting precipitates were collected by filtration, followed by recrystallization from ethanol to obtain 0.4 g of a pale yellow solid, m.p. 235° to 237° C.

Workup

  1. waitthe solution was left
  2. customresulting
  3. customprecipitates
  4. filtrationwere collected by filtration
  5. customfollowed by recrystallization from ethanol

Sources & evidence

ORD record
ord-b42a5898d7fd419fbaaea080a334e370
Source dataset
uspto-grants-1989_02
Patent number
US04804665

Reaction notes

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