HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2,4-dichloro-5-(1-methylethoxy)phenyl]-3-difluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one → 1-(2,4-dichloro-5-hydroxyphenyl)-3-difluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2,4-dichloro-5-(1-methylethoxy)phenyl]-3-difluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one | HCID 14392486 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 1-(2,4-dichloro-5-hydroxyphenyl)-3-difluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one | HCID 14392487 | 71.7% |
Reaction Steps
Hydrolysis of 2.2 g (0.0063 mole) of 1-[2,4-dichloro-5-(1-methylethoxy)phenyl]-3-difluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one in 5 mL of concentrated sulfuric acid produced 1.4 g of 1-(2,4-dichloro-5-hydroxyphenyl)-3-difluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one (mp 176°-179° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806145 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-a47ace8a2d7f4a1da3dfdff34b7165fe |
| Source note | uspto-grants-1989_02 |