Hydrazine hydrate (1:1) → HCID 14581294, compound

Participants

Reaction Steps

A solution of 0.43 g (1.4 mmol) of 3-[4-(1H-imidazol-1-yl)benzoyl]-4-carbomethoxypyridine in 50 mL of EtOH is treated with hydrazine monohydrate (0.08 g, 1.54 mmol) and heated to reflux for 1 day. The mixture is allowed to cool and the white solid precipitate filtered and dried to produce 4-[4-(1H-imidazol-1-yl)phenyl]-1-oxo-1,2-dihydropyrido[3,4-d]pyridazine. M.P. 377° C. dec.

Provenance & Evidence