Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 53702544 | HCID 53702544 | — |
| Catalyst | Silver(II) oxide | HCID 92152 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 54523016 | HCID 54523016 | — |
Reaction Steps
10 mg of methyl 11-(3-hydroxymethyl-4-oxo-2-oxetanyl)-4,5-dihydroxy-3,5,7-trimethyl-2-undecenoate in 2 ml of EtOAc was added 35 mg of silver oxide and 0.3 ml of methyl iodide. The mixture was heated at 53° C. overnight. The solution was filtered and concentrated by dryness. The product was purified by prep. TLC (EtOAc:Hexane=1:1) to afford methyl 11-(3-methoxymethyl-4-oxo-2-oxetanyl)-4,5-dihydroxy-3,5,7-trimethyl-2-undecenoate. ##STR26##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04806564 |
|---|
| Source dataset | uspto-grants-1989_02 |
|---|
| ORD ID | ord-131b8f9314f74cf58613da190d7a20d2 |
|---|
| Source note | uspto-grants-1989_02 |
|---|
