HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → 1-(2-Methoxyphenoxy)-4-(4-phenyl-1-piperazinyl)-2-butanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Chloro-1-(2-methoxyphenoxy)-2-butanol | HCID 13120350 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-(2-Methoxyphenoxy)-4-(4-phenyl-1-piperazinyl)-2-butanol | HCID 14422873 | 64% |
Reaction Steps
This compound was prepared according to the procedure of Example 78. A mixture of 3.2 g (0.02 mole) of 1-phenylpiperazine, 4.8 g (0.02 mole) of 4-chloro-1-(2-methoxyphenoxy)-2-butanol and 8.0 g (0.075 mole) of anhydrous sodium carbonate in 100 ml of 1-butanol gave 4.5 g (64%) of white powder, m.p. 101°-102° C. Recrystallizing solvent used was iropropyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806555 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-a29779eaf3474e9b8cc6978136ef45cd |
| Source note | uspto-grants-1989_02 |