HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzamide, N-cyano- → HCID 178512389, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzamide, N-cyano- | HCID 84805 | — |
| Reactant | 4-Amino-1-(2-naphthyl)methylpiperidine | HCID 11195823 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 178512389 | HCID 178512389 | 40.4% |
Reaction Steps
4-Amino-1-(naphth-2-ylmethyl)piperidine (1.0 g, 0.0042 m) and benzoyl cyanamide (0.67 g, 0.0042 m) in toluene (100 cm3) were refluxed for 15 hours. The solvent was evaporated and the residue recrystallised from the minimum amount of isopropyl alcohol and recrystallised twice more from ethanol to give 0.65 g of the title compound, m.p. dihydrochloride quarter hydrate, m.p. 260°-262° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806552 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-8dae87f3430247cfba9c9f42b16f3681 |
| Source note | uspto-grants-1989_02 |