Ammonia → 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-1-(1-methyl-4-piperidinyl)-5-phenyl-

HRID 138247Notes

Reaction equation

HRID 138247 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[c:10]([C:15]([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)=[N:22][CH2:23][C:24]([O:26][CH2:25][CH3:27])=[O:28])[cH:11][cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1.[NH3:30].[OH2:29].[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([N:8]2[c:9]3[c:10]([cH:11][cH:12][cH:13][cH:14]3)[C:15]([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)=[N:22][CH2:23][C:24]2=[O:26])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 222AmmoniaHCID 962WaterHCID 6422Trifluoroacetic acidHCID 13450681HCID 13450681, compound

Product 1

HCID 566582H-1,4-Benzodiazepin-2-one, 1,3-dihydro-1-(1-methyl-4-piperidinyl)-5-phenyl-

Sources & evidence

ORD record
ord-c60a599f04d24c1aa425ef6452726a3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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