Acetone → HCID 23437540, compound

HRID 1382478Notes

Reaction equation

HRID 1382478 reaction equation
C([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]([NH:12][C:13](=[O:15])[CH:14]=2)=[O:11])=[CH:5][CH:4]=1)#C.NC1C=CC=CC=1[OH:23].CC(C)=O.C(OC(=O)C)(=O)C>C([O-])(=O)C.[Ni+2].C([O-])(=O)C.C(N(CC)CC)C>[OH:23][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]([NH:12][C:13](=[O:15])[CH:14]=2)=[O:11])=[CH:5][CH:4]=1

Participants

7

Reactant 4

HCID 180AcetoneHCID 58012-AminophenolHCID 7918Acetic AnhydrideHCID 19853730HCID 19853730, compound

Product 1

HCID 23437540HCID 23437540, compound

Reagents, catalysts & solvents 2

HCID 9756Nickel AcetateCatalystHCID 8471TriethylamineSolvent

Procedure

4-hydroxyphenyl maleimide was prepared by the same procedure as for 4-ethynylphenyl maleimide with the following starting materials aminophenol (54.5 g, 0.50 mole) maleic anhydride (49.0 g, 0.50 mole), acetone (500 ml), triethylamine (11 ml), nickel (II) acetate (0.5 g, 43 mmol), and acetic anhydride (63.8 g, 0.625 mol).

Sources & evidence

ORD record
ord-5dd7cc9636ec49a98ef949309a27d183
Source dataset
uspto-grants-1989_02
Patent number
US04806608

Reaction notes

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